ISD RESEARCH

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Brain Imaging and Biomarker Research Group

Research Group – PI: Michael Ewers

Research Focus Publications Team

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2-image — The choroid plexus is a key cerebral invasion route for T cells after stroke.

ISD researchers have identified the choroid plexus as a previously unrecognized key structure for cerebral T cell invasion into the brain after stroke. These findings are of high relevance for clinical trials targeting immune cell infiltration in stroke patients...

1-image — Novel Risk Loci for Alzheimer's Disease

A multinational consortium including ISD researchers identified rare coding variants associated with Alzheimer's disease (AD). The variants are situated in genes that are highly expressed in microglia and highlight a role of microglia-mediated innate immune responses in AD...

1-image — miRNA set as a novel biomarker for ischemic stroke

Using RNA sequencing and qRT-PCR in three independent samples of acute ischemic stroke patients ISD researchers established a set of 3 circulating microRNAs (miR-125a-5p, miR-125b-5p and miR-143-3p) as a promising blood-based diagnostic marker for the early phase of ischemic stroke...